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Efficacy and Safety Preclinical Services to Accelerate Research Needs

Altogen Labs, a global biology CRO company, provides preclinical research services for pharmaceutical, biotechnology, and cancer research centers worldwide. In an effort to expedite the development of new anti-cancer medicines, Altogen Labs now provides over 100 in-house validated xenograft models and safety in vivo toxicology services for drug development studies.

Both efficacy and safety studies are crucial in the process of new drug development. Efficacy studies aim to evaluate if the drug has the intended effect under ideal circumstances, determine the optimal dosages, type of administration, and the duration of treatment. On the other hand, safety studies assess potential risks and side effects associated with the novel drug. Such studies are designed to understand the test article toxicity, its effect on different organ systems, and any adverse reactions it may cause. Together, these non-clinical studies ensure that a new drug candidate is both effective in treating the condition it’s designed for and safe for consumption.

Altogen Labs offers both efficacy and safety studies that are required for new drug development. These laboratory studies focus on various areas including cancer, inflammation, pain and neurodegenerative diseases, immunology and obesity. Pre-clinical trials are crucial for assessing the toxicity and pharmacological activity of investigative new drugs (INDs) to evaluate a compound’s potential therapeutic benefits and safety for human use. Altogen Labs laboratory services include xenograft TGD and in vivo toxicology studies for IND applications, biodistribution and imaging studies, RNAi and gene expression studies, development of stable cell lines and tissue culture testing services.

About Altogen Labs

Altogen Labs is a GLP compliant contract research organization (CRO) providing preclinical research services to pharmaceutical companies, biotechnology firms, and academic institutions worldwide. Altogen Labs is headquartered in Austin, Texas. For more information about our services please visit our website at altogenlabs.com

Contact

Alex Fanelli | alex.fanelli@altogenlabs.com

Altogen Labs | 11200 Menchaca Rd Ste 203, Austin TX 78748 USA

Tel: 512-433-6177 | Web: altogenlabs.com

Array of Lung Cancer Xenograft Models for Cutting-Edge Oncology Research

Altogen Labs, a preclinical CRO laboratory, has announced the validation of a comprehensive array of 10 lung cancer xenograft models. These models are essential for testing in vivo efficacy of novel therapeutics against lung cancer, elevating the prospects for significant advances in the diagnosis, understanding, and treatment of primary lung carcinoma. Less than 20% of… Continue Reading

Validated preclinical xenograft models for in vivo efficacy testing of INDs

Altogen Labs provides validated preclinical xenograft models for in vivo efficacy testing of Investigational New Drugs (INDs). These research services are conducted under Good Laboratory Practices (GLP) standards. The xenograft models are rigorously validated to ensure reliable and reproducible results. Altogen Labs offers a wide selection of validated CDX and PDX xenograft models, including many… Continue Reading

Toxicology IND Preclinical Research Services

Toxicology IND Preclinical Research Services

Altogen Labs, a preclinical CRO, provides essential safety and efficacy testing for novel medicines (GLP-compliant pharm/tox assays per FDA IND requirements). Company works with renowned academic research organizations and pharma/biotech industry to reduce GLP studies timelines and costs while maintaining high quality and GLP standards. Altogen Labs preclinical CRO services includes efficacy xenograft studies (over… Continue Reading

Validated breast cancer xenograft models

Altogen Labs is a GLP-compliant biotech laboratory that specializes in oncology research studies and provides preclinical testing of new medicines that often require a sequence of experiments utilizing various scientific methods to demonstrate novel compound anti-cancer efficacy, safety, and mechanism of action. Breast cancer is the second leading cancer that causes death in women globally,… Continue Reading

Science Calculators

More calculators and articles at Altogen Labs | Scientific Resources webpage Validated xenograft models: Xenograft Models | Altogen Labs More calculators and articles at Altogen Labs | Scientific Resources webpage Validated xenograft models: Xenograft Models | Altogen Labs More calculators and articles at Altogen Labs | Scientific Resources webpage Validated xenograft models: Xenograft Models |… Continue Reading

100+ Validated Xenograft Models for In Vivo IND Efficacy Testing. Preclinical GLP Research Services by Altogen Labs.

100+ Validated Xenograft Models for In Vivo IND Efficacy Testing. Preclinical GLP Research Services by Altogen Labs.

AUSTIN, Texas – July 28, 2021 – Altogen Labs offers over 100 validated models of cell line-derived xenografts (CDX) and patient-derived xenografts (PDX), including syngeneic xenograft models. Xenograft IND testing services are performed to measure the activity and efficacy of novel anti-cancer compounds based on the rate of engrafted tumor growth. The most recent additions… Continue Reading

Altogen Laboratory Testing of Known Compounds for Cancer Treatment Efficacy

Sodium dichloroacetate (DCA) has been investigated as a novel cancer therapy since 2007 when Bonnet et al published research study demonstrating the efficacy of DCA in treating human cancers by inhibition of mitochondrial pyruvate dehydrogenase kinase (PDK). Altogen Labs, an Austin-based biotechnology and preclinical research company, performed an independent study exploring potential novel and accessible… Continue Reading

How to test the anticancer efficacy of a plant extract

Testing the anticancer efficacy of a plant extract involves a series of in vitro (using cancer cell lines) and in vivo (animal-based) experiments, as well as testing safety and efficacy. The process can be lengthy and requires adherence to scientific and ethical guidelines. Here is an outline of the general procedure: Altogen Labs provides commercially… Continue Reading

Next-Day PCR Rapid Test COVID-19

Altogen Labs is now offering expedited PCR analysis services for most variants of COVID-19, including the highly transmissible Omicron variant. Results are guaranteed the next day. The price for this service is $250. Altogen Labs offers PCR tests only. How does it work? Submitting your sample for PCR testing at Altogen Labs is done at… Continue Reading