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AUSTIN, Texas – April 20, 2024 – Altogen Labs has published details of its in vitro toxicology and genotoxicity service portfolio, giving sponsors access to early safety signals well before an in vivo program is committed. Genotoxicity liabilities discovered late are among the most expensive failures in drug development. Altogen Labs performs micronucleus and comet… Continue Reading
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Altogen Labs Listed Among Biology CRO Members of the Medical Technology Consortium
AUSTIN, Texas – February 17, 2024 – Altogen Labs, a leading contract research organization specializing in preclinical research services for pharmaceutical, biotechnology, and academic institutions worldwide, joined Medical Technology Consortium. Altogen Labs’ focus areas as oncology, gene silencing, xenograft models, and advanced biotechnology services including stable cell line development, RNA interference, and in vivo imaging.… Continue Reading
Altogen Labs Lung Cancer Xenograft Models Portfolio
AUSTIN, Texas – November 9, 2023 – The validation of ten in-house lung cancer xenograft models by Altogen Labs has been carried by pharmaceutical and biopharma trade media internationally, extending awareness of the company’s oncology model portfolio to drug development audiences across North America, Europe, and Asia. The announcement drew attention because the underlying problem… Continue Reading
Array of Lung Cancer Xenograft Models for Cutting-Edge Oncology Research
Altogen Labs, a preclinical CRO laboratory, has announced the validation of a comprehensive array of 10 lung cancer xenograft models. These models are essential for testing in vivo efficacy of novel therapeutics against lung cancer, elevating the prospects for significant advances in the diagnosis, understanding, and treatment of primary lung carcinoma. Less than 20% of… Continue Reading
Altogen Labs Bioluminescent Imaging Enables Real-Time Tracking of Orthotopic and Metastatic Tumor Growth
AUSTIN, Texas – August 1, 2023 – Altogen Labs today highlighted its in vivo bioluminescent imaging capability, which allows sponsors to track internal orthotopic and metastatic tumor growth in real time rather than relying on end-of-study tumor weight. In a published Altogen Labs case study, a luciferase-expressing U87-Luc glioma cell line was used to monitor… Continue Reading
Validated preclinical xenograft models for in vivo efficacy testing of INDs
Altogen Labs provides validated preclinical xenograft models for in vivo efficacy testing of Investigational New Drugs (INDs). These research services are conducted under Good Laboratory Practices (GLP) standards. The xenograft models are rigorously validated to ensure reliable and reproducible results. Altogen Labs offers a wide selection of validated CDX and PDX xenograft models, including many… Continue Reading
Toxicology IND Preclinical Research Services
Altogen Labs, a preclinical CRO, provides essential safety and efficacy testing for novel medicines (GLP-compliant pharm/tox assays per FDA IND requirements). Company works with renowned academic research organizations and pharma/biotech industry to reduce GLP studies timelines and costs while maintaining high quality and GLP standards. Altogen Labs preclinical CRO services includes efficacy xenograft studies (over… Continue Reading
Validated breast cancer xenograft models
Altogen Labs is a GLP-compliant biotech laboratory that specializes in oncology research studies and provides preclinical testing of new medicines that often require a sequence of experiments utilizing various scientific methods to demonstrate novel compound anti-cancer efficacy, safety, and mechanism of action. Breast cancer is the second leading cancer that causes death in women globally,… Continue Reading
Science Calculators
More calculators and articles at Altogen Labs | Scientific Resources webpage Validated xenograft models: Xenograft Models | Altogen Labs More calculators and articles at Altogen Labs | Scientific Resources webpage Validated xenograft models: Xenograft Models | Altogen Labs More calculators and articles at Altogen Labs | Scientific Resources webpage Validated xenograft models: Xenograft Models |… Continue Reading
Altogen Labs Preclinical Research Indexed in Global Life Science Reference Databases
AUSTIN, Texas – March 14, 2023 – Research generated at Altogen Labs has been indexed within many citation databases including Sigma-Aldrich (Merck KGaA) where the company’s glioblastoma study appears among the validating references associated with pyruvate dehydrogenase kinase (PDK) detection reagents. The underlying study, published in Cancer Biology & Therapy, evaluated eight structurally modified dichloroacetate analogs… Continue Reading