Xenograft Animal Service

Altogen Labs provides over 50 xenograft cancer animal models (biodistribution, PK/PD, imaging studies). We offer assistance in choosing the best model suitable for clients experimental goals. Animal handling and maintenance at our facility is IACUC-regulated and GLP-compliant. We provide detailed experiment procedures, health reports and experimental data.

In Vivo siRNA Delivery

Altogen Labs provides A-to-Z RNAi in vivo delivery services: custom si/miRNA liposome encapsulation, chemical modification, in vitro validation, in vivo tissue-targeted delivery. Assays include: oligonucleotide accumulation (TaqMan), target mRNA (RT-PCR) and protein expression levels (WB and ELISA).

Generation of Stable Cell Line

Stable cell lines over-expressing a protein of interest, or RNAi construct targeting a gene of interest, are powerful research tools for the production of recombinant antibodies, drug screening, and gene function studies. Altogen Labs provides service of stable cell line development completed in 28 days.

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Pre-clinical CRO Services: Xenograft Studies, IC50, Pharm/Tox Assays

Altogen Labs is a Good Laboratory Practice (GLP)-compliant laboratory that provides biotechnology research services for pharmaceutical, biotechnology, and academic institutions worldwide. Our services include safety in vivo toxicology studies (for IND applications), efficacy studies (for regulatory submissions), drug discovery (patent applications), drug development and other types of R&D studies – pharm/tox, biodistribution and imaging studies. We provide a variety of biology CRO laboratory in vitro and in vivo services, including IC-50 assays, development of stable cell lines, over 50 xenograft animal models, gene function and gene expression analysis (mRNA levels by qPCR and protein expression by Western Blot), in vivo RNAi and tissue-targeted siRNA delivery services, transient and stable transfections, development of RNAi knockdown cell lines, anti-cancer compound testing, microfluidics-based liposome encapsulation (protein, DNA, siRNA, small molecule), cell-based assay development.

Preclinical research studies often require a sequence of experiments utilizing various scientific methods to demonstrate novel compound efficacy, safety, and mechanism of action. Altogen scientists have years of experience and expertise that includes all types of preclinical and biology CRO studies, cell and molecular biology research and development services, pharmacology and toxicology safety studies. We provide a wide range of GLP-compliant contract research laboratory services to meet clients’ unique needs, including stable cell line development in 28 days, A-to-Z complete RNAi services (from oligonucleotide design and synthesis to tissue-targeted delivery), compound custom liposome encapsulation, and cell banking services. Technical support and quality control teams ensure and support the company’s high-quality products and services. We support clients from study design phase through patent or regulatory submissions (100% of IP belongs to the client).

Altogen Labs offers instant quotes (info@altogenlabs.com, or call us at 512-433-6177), comprehensive service packages, and highly competitive prices. We are happy to discuss your experimental details to help generate accurate price quotes and timeline estimates.