Xenograft Animal Service

Altogen Labs offers assistance in choosing the best model suitable for clients experimental goals. Animal handling and maintenance at our facility is IACUC-regulated and GLP-compliant. We provide detailed experiment procedures, health reports and experimental data.

In Vivo siRNA Delivery

Most often, these effects are induced by the introduction of small-interfering RNA (siRNA) or microRNA (miRNA). A siRNA molecule is double-stranded and 20-24 base pairs in length, terminating in two overhanging nucletoides with phosphorylated 5' and hydroxylated 3' ends.

Generation of Stable Cell Line

Stable cell lines over-expressing a protein of interest (or shRNA construct targeting a gene of interest) are important research tools, particularly for the production of recombinant antibodies and other proteins, the study of gene functions, drug screening, and other applications.

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Pre-clinical CRO Services – Xenograft, IC50, Pharm/Tox Studies

Altogen Labs is a Good Laboratory Practice (GLP)-compliant laboratory that provides biotechnology research services for pharmaceutical, biotechnology, and academic institutions worldwide. Our services include all types of laboratory CRO pre-clinical research, including generation of stable cell lines and tissue culture testing services, IC-50 assay development, in vivo toxicology studies for IND applications, biodistribution studies (rodents) and xenograft animal models, gene expression analysis (mRNA levels by qPCR and protein expression by Western Blot), tissue-targeted in vivo RNAi and siRNA delivery services, transient and stable transfection, development of RNAi knockdown cell lines, anti-cancer compound testing (in vitro and in vivo), microfluidics-based liposome encapsulation (proteins, DNA, siRNA, small molecule), gene silencing and cell-based assay development (apoptosis, cell viability, cell cycle, ATP), microorganism ID and 16S sequencing, bacteria identification and bioinformatic analysis services.

Altogen scientists have years of experience and expertise that includes all types of pre-clinical CRO studies, cell and molecular biology research and development. We provide a wide range of GLP-compliant contract research laboratory services to meet clients’ unique needs, including A-to-Z stable cell line development, RNAi and cell banking services. Technical support and quality control teams ensure and support the company’s high-quality products and services.

Altogen Labs offers instant quotes (info@altogenlabs.com, or call us at 512-433-6177), comprehensive service packages, and highly competitive prices. We are happy to discuss your experimental details to help generate accurate price quotes and timeline estimates.