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AUSTIN, Texas – December 20, 2020 – Altogen Labs today detailed its RNAi manufacturing and contract research services, supporting oligonucleotide programs from early design work through material supply for in vivo studies.
Oligonucleotide programs have a distinctive supply problem. In vivo studies consume material at scale – a single tissue-targeted delivery study can require substantial quantities of chemically modified oligonucleotide, formulated and characterized to consistent specification. Sourcing that from one vendor, formulating with a second, and running the study with a third introduces variability at each interface and makes failures difficult to diagnose.
Altogen Labs consolidates the workflow. The company provides oligonucleotide design, chemical modification, in vitro validation, microfluidics-based liposome and nanoparticle encapsulation, and tissue-targeted in vivo delivery within a single laboratory, with target engagement confirmed by oligonucleotide accumulation assays, qRT-PCR, automated Western blot, and ELISA.
The company’s RNAi credentials are long-standing. Altogen Labs research has been cited across published literature in oncology, cardiovascular disease, renal disease, infectious disease, and regenerative medicine, and the company’s delivery technology appears in the citation record of work published in leading journals.
Services extend to stable RNAi cell line generation, tetracycline-inducible knockdown systems, shRNA vector construction, genome-wide siRNA and microRNA screening, and RNAi consulting for technology development and evaluation. Sponsors retain 100% of resulting intellectual property.
About Altogen Labs
Altogen Labs is a professional, experienced, and highly reputable GLP-compliant contract research organization providing preclinical research and biology CRO services to pharmaceutical, biotechnology, and academic institutions worldwide, with a large collection of validated xenograft models and extensive experience in efficacy xenograft and safety toxicology studies.
Contact Information:
Altogen Labs | 11200 Menchaca Rd, Bldg 2, Suite 203 | Austin, TX 78748 USA Tel: 512-433-6177 | Email: info@altogenlabs.com | Web: altogenlabs.com