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AUSTIN, Texas – March 12, 2013 – Altogen Labs today highlighted its adipogenesis stimulation assay service, supporting sponsors working in obesity, diabetes, and metabolic disease.
Metabolic disease programs need functional assays that report on adipocyte biology directly rather than inferring it from systemic markers. The adipogenesis stimulation assay provides that readout, allowing compounds to be evaluated for their effect on adipocyte differentiation and lipid accumulation.
The service sits within a broader non-oncology capability that many sponsors do not associate with Altogen Labs. In addition to cancer research, the company conducts preclinical studies in inflammation, immunology, neurodegenerative disease, pain, infectious disease, diabetes, and obesity, supported by the same GLP-compliant infrastructure that underpins its oncology work.
Metabolic programs can access in vivo toxicology across acute, sub-chronic, and chronic designs, OECD-guideline safety studies, PK/PD and biodistribution, tissue-targeted in vivo RNAi delivery for target validation in liver and adipose tissue, gene expression analysis by RT-PCR, protein quantification by automated capillary Western, ELISA-based biomarker panels, and histopathology.
Published research using Altogen delivery technology has reported successful modulation of regulatory RNAs in cardiac and renal tissue in disease models, demonstrating that the platform performs in the metabolic and cardiovascular setting as well as in oncology. All studies are conducted by experienced scientists at the company’s GLP-compliant, IACUC-regulated Austin, Texas facility.
About Altogen Labs
Altogen Labs is a professional, experienced, and highly reputable GLP-compliant contract research organization providing preclinical research and biology CRO services to pharmaceutical, biotechnology, and academic institutions worldwide, with a large collection of validated xenograft models (altogenlabs.com/xenograft-models) and extensive experience in efficacy xenograft and safety toxicology studies.
Contact Information:
Altogen Labs | 11200 Menchaca Rd, Bldg 2, Suite 203 | Austin, TX 78748 USA Tel: 512-433-6177 | Email: info@altogenlabs.com | Web: altogenlabs.com